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Antimony is a non-essential element in humans, animals and plants. Its toxicity highly depends upon chemical form and oxidation state with +III compounds exerting greater toxicity than +V compounds. Antimony compounds show toxic properties similar to those of arsenic.
procedures for antimony and antimony compounds for pulmonary toxicity, cancer and genotoxicity. As reviewed by ATSDR, 2019 the uptake of antimony into the body can be dominated by the inhalation exposure route. Uptake from the gastrointestinal tract is low (<1%) and self-limited by the emetic properties of antimony compounds (ATSDR, 2019).
Antimony toxicity occurs either due to occupational exposure or during therapy. Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on the skin and gastrointestinal symptoms. In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working conditions have remarkably decreased the incidence of antimony toxicity in the workplace.
Thomas W. Clarkson, in Handbook of Pesticide Toxicology (Second Edition), 2001 61.11.1.3 Toxicity to Humans Therapeutic Use. When antimony potassium tartrate is rubbed on the skin in the form of an ointment, it produces little irritation at first but produces a pustular eruption if applied for long periods. This is due to decomposition of the double salt by the acid secretions of the follicles ...
Toxicity results from the body's natural breakdown of nitrate to nitrite. Causes "bluebaby disease," or methemoglobinemia, which threatens oxygen-carrying capacity of the blood. Selenium: Enters environment from naturally occurring geologic sources, sulfur, and coal. Causes acute and chronic toxic effects in animals--"blind staggers" in cattle.
potential targets of antimony toxicity, although the relevance to environmental exposure is not known . ANTIMONY AND COMPOUNDS 13 2. HEALTH EFFECTS . given the poor absorption of antimony compounds following inhalation, oral, or dermal exposure (see Section 3.1.1). The primary targets of toxicity appear to the heart (alterations in EKG readings),
Antimony in the Body. The major toxic side-effects of antimonials as a result of therapy are cardiotoxicity (~9% of patients) and pancreatitis, which is seen commonly in HIV and visceral leishmaniasis co-infections. Low doses cause headaches, nausea, dizziness and depression. Large doses cause vomiting, diarrhea, abdominal discomfort and ...
Toxicity Data: Antimony trichloride LD50 (oral, rat) 525 mg/kg Component NTP Listing IARC Listing OSHA Regulated Antimony trichloride No listing No listing ACGIH TLV: STELTWA Ceiling Antimony trichloride (as Sb) 0.5 NEmg/m3 NE EMERGENCY FIRST AID PROCEDURES Additional First Aid and Treatment Notes: No information available
Health Concerns. If you think you may be experiencing symptoms from exposure to a bloom, contact your health care provider or call the Utah Poison Control Center:. 1-800-222-1222. If you think your pets or other animals may be experiencing symptoms, contact your veterinarian.
Antimony is a naturally occurring metal often used in combination with lead and zinc, found in metal alloys, paints, ceramics, and fireworks. It is also used as a catalyst to produce polyester, and is found in plastics used for disposable beverage bottles. The most widely used antimony compound is antimony trioxide, used as a component in flame retardant applications.
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T56.891A is a billable diagnosis code used to specify a medical diagnosis of toxic effect of other metals, accidental (unintentional), initial encounter. The code T56.891A is valid during the fiscal year 2022 from October 01, 2021 through September 30, 2022 for the submission of HIPAA-covered transactions.
Toxic effects on the kidney may follow chronic use. Continuous treatment with small doses of antimony may give rise to symptoms of subacute poisoning, similar to those of chronic arsenic poisoning, due to accumulation of antimony in the body, especially if trivalent compounds are used, because of their long biological half-lives.
A Brief History of Poisoning | Classic Poisons | Infamous Historical Poisoners. The dose makes the poison, Paracelsus once said. And there is no truer statement about the nature of poisons. The toxicity of many medicinal substances were discovered only when a slip of the hand or experiments driven by curiosity revealed the lethality of these substances in large (or, in the case of antimony ...
potential targets of antimony toxicity, although the relevance to environmental exposure is not known . ANTIMONY AND COMPOUNDS 13 2. HEALTH EFFECTS . given the poor absorption of antimony compounds following inhalation, oral, or dermal exposure (see Section 3.1.1). The primary targets of toxicity appear to the heart (alterations in EKG readings),
* Antimony Trioxide may damage the kidneys, liver and heart. IDENTIFICATION Antimony Trioxide is a white, odorless crystalline (sand-like) powder. It is used as a flame-proofing agent, in pigments and ceramics, to stain iron and copper, and to decolorize glass. REASON FOR CITATION * Antimony Trioxide is on the Hazardous Substance List
CLINICAL IMPLICATIONS: Antimonial compounds are still used in treatment of Leishmaniasis with cardiac toxicity being one of the known potential side effects. Ventricular myocytes of guinea-pigs treated with trivalent antimony showed impaired contraction responses to changes in stimulus frequency, reduced calcium current, and elongated action potential.
Synonyms for antimony poisoning in Free Thesaurus. Antonyms for antimony poisoning. 2 synonyms for antimony: atomic number 51, Sb. What are synonyms for antimony poisoning?
Antimony is an element with atomic symbol Sb, atomic number 51, and atomic weight 121.76. NCI Thesaurus (NCIt) Antimony powder appears as a silvery or gray solid in the form of dust. Denser than water and insoluble in water. Toxic by inhalation and by ingestion.
Antimony (Sb) is a silver-white brittle solid or a dark-gray, lustrous powder. It can be harmful to the eyes and skin. Antimony can also cause problems with the lungs, heart, and stomach. Workers may be harmed from exposure to antimony and its compounds. The level of exposure depends upon the dose, duration, and work being done.
Antimony has been used in antihelminthic drugs in the treatment of schistosomiasis. Side effects of these medications include myocarditis, pericardial effusion, and other electrocardiographic abnormalities. Rarely these adverse effects can be as serious as bradycardia, ventricular arrhythmias, and sudden death. Environment.
Antimony (Sb) is a naturally occurring metal that is used in various manufacturing processes. It exists in valence states of 3 and 5 (Budavari, 1989; ATSDR, 1990). Antimony is a common urban air pollutant (Beliles, 1979). Exposure to antimony may be …
l EPA/690/R-08/004F Final 8-5-2008. Provisional Peer Reviewed Toxicity Values for . Antimony Trioxide (CASRN ) Superfund Health Risk Technical Support Center
Carcinogenic, mutagenic and reprotoxic substances are often referred to as a group, due to the fact that a substance may present all three types of hazards but also due to similarities in classification and in legal approach. The abbreviation 'CMR' is also commonly used. CMRs are chronically toxic and have very serious impacts on health.
ANTIMONY AND COMPOUNDS ii . DISCLAIMER . Use of trade names is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry, the Public Health Service, or the U.S. Department of Health and Human Services.
Vitamin C deficiency – Frequent colds, lack of energy, frequent infections, bleeding or tender gums, easy bruising, nosebleed, slow wound healing, red pimples on skin can all be indications of antimony toxicity. Vitamin B3 deficiency – Lack of energy, diarrhea, insomnia, headaches or migraines, poor memory, anxiety or tension, depression ...
Toxic dose. The lethal oral dose of metallic antimony in rats is 100 mg/kg of body weight; the trivalent and pentavalent oxides are less toxic, with LD 50 in rats ranging from 3200–4000 mg/kg of body weight. The recommended workplace limit (ACGIH TLV-TWA) for antimony is 0.5 mg/m 3 as an 8-hour time-weighted average.
Source: The Health Dangers of Antimony by Dr. Edward Group Antimony is a naturally occurring metal typically found in ore deposits. [1] Antimony is widely used in industry and present in all kinds of everyday items. Most commonly, the metal has been used as a flame retardant in products as diverse as toys, car seat covers,…
Mercury, chromates, sulfides, barium and antimony are just some of the other toxic ingredients that were used to create oil paints. The popular Cadmium Reds, Oranges, and Yellows contained cadmium, while cobalt contributed to Cobalt Blue and Cerulean Blue. Scheele's Green rose to popularity in the 19th century, replacing the previous green ...
Antimony poisoning also shares features common with other metal poisonings, described in the chapters that follow. Although relatively uncommon, antimony toxicity occurs, usually as a complication of the treatment of visceral leishmaniasis. 101 Acute overdose represents an even rarer, but potentially lethal event, most often recently as a ...
