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CardioGen-82 contains accelerator-produced Sr-82 adsorbed on stannic oxide in a lead-shielded column and provides a means for obtaining sterile nonpyrogenic solutions of rubidium Rb 82 chloride injection. The chemical form of Rb-82 is 82 RbCl. The amount (millicuries) of Rb-82 obtained in each elution will depend on the potency of the generator.

"Last Elution Date" and "Last Elution Time" must be entered for each calculation. It is assumed that each generator is eluted at the manufacturing facility prior to shipping. This should be taken into account when calculating the amount of Tc-99m in-growth prior to first use. Suggested times for factory test elutions:

CARDIOGEN-82 ® (Rubidium Rb 82 Generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous administration. Rubidium Rb 82 chloride injection is …

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The chemical form of Rb 82 is 82 RbCl. The amount (mCi) of Rb 82 obtained in each elution will depend on the potency of the generator. When used with the RUBY Rubidium Elution System, the generator provides ± 10% accuracy for rubidium Rb 82 chloride doses between 370-2220 MBq (10-60 mCi). When eluted at a rate of 15 -30 mL/minute, each ...

Cardiogen-82 (rubidium Rb 82 generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous administration. Rubidium Rb 82 chloride injection is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing …

2.1 Radiation Safety - Drug Handling. Rubidium Rb 82 is a radioactive drug and should be handled with appropriate safety measures to minimize radiation exposure during administration [See Warnings and Precautions ].. Use only additive-free 0.9% Sodium Chloride Injection USP to elute the generator [see Boxed Warning, Contraindications, and Warnings and Precautions ].

Rubidium-82 (82 Rb) is a widely used positron emission tomography (PET) tracer with a short half-life of ~ 75 seconds.1 Stress perfusion imaging with 82 Rb is used widely in cardiac PET centers for the assessment of known or suspected coronary artery disease.2 The short half-life of 82 Rb allows rapid sequential rest and stress imaging with low-radiation exposure to patients and medical …

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Rubidium-82 chloride (Rb-82) (T 1/2 = 75 sec) is a chemical analog of Tl-201 chloride used for the assessment of coronary artery disease with PET. 19, 33 Rb-82 is produced as the daughter radionuclide of strontium-82 (Sr-82) eluted from a portable on-site generator renewed approximately monthly due to the physical half-life of Sr-82 (T 1/2 = 25 ...

An 82 Sr/ 82 Rb generator column is made using a fluid impervious cylindrical container having a cover for closing the container in a fluid tight seal, and further having an inlet for connection of a conduit for delivering a fluid into the container and an outlet for connection of a conduit for conducting the fluid from the container. An ion exchange material fills the container, the ion ...

Returns the value of attribute klass_names. #root ⇒ Object root ⇒ Object . Returns the value of attribute root.

The Rubidium Elution System has been exclusively designed for use with the RUBY-FILL® Rubidium 82 Generator and to deliver accurate doses of Rb-82 Chloride to patients. Indication for Use. RUBY-FILL is a closed system used to produce rubidium Rb 82 chloride injection for intravenous use.

The generator yield (82 Rb) and production efficiency (82 Rb yield/ 82 Sr parent activity) were measured and compared after this conversion to a common scale. Results: At the start of clinical use, the system reported 82 Rb activity from daily QA was lower for CardioGen-82 ® vs RUBY-FILL ® (2.3 ± 0.2 vs 3.0 ± 0.2 GBq, P < 0.001) despite ...

CARDIOGEN-82® (Rubidium Rb 82 Generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous administration. Rubidium Rb 82 chloride injection is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the myocardium under

CardioGen-82 ® (Rubidium Rb 82 Generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous administration. Rubidium Rb 82 chloride injection is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing ...

Rubidium-82 is produced through beta plus decay from its parent nucleus, strontium-82.The generator contains accelerator produced 82 Sr adsorbed on stannic oxide in a lead-shielded column and provides a means for obtaining sterile nonpyrogenic solutions of RbCl(Halide salt form capable of injection). The amount (millicuries) of 82 Rb obtained in each elution will depend on the potency of the ...

1) Record each generator eluate volume, including waste and test volumes, and keep a record of the cumulative eluate volume [see Dosage and Administration (2.4)]. 2) Determine Rb-82, Sr-82, Sr-85 in the generator eluate: Once a day, prior to any drug administrations, and At additional daily tests after detection of an Alert Limit.

3 CardioGen-82® INDICATIONS TM Indications and Usage:1 CARDIOGEN-82® (Rubidium Rb 82 Generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous administration. Rubidium Rb 82 chloride injection is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the myocardium under

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Rubidium-82 ((82)Rb) is a generator-produced PET myocardial perfusion tracer and has been widely used in North America in clinical practice. (82)Rb PET has recently become available in some cardiovascular centers in Europe and Japan. Clinical trials are expected in both regions.

rubidium strontium generator support medium water Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Granted Application number EP85401599A Other languages German (de) French (fr)